Senario #1 - So character A and character B have been in a relationship for awhile now and at some point one of them becomes blind so now the other has to help them adapt to not being able to see anything

Senario #2 - Character A is a werewolf and they eventually meet character B and fall in love and all that fun stuff, but they soon learn that character B has some family that happen to hunt werewolves (Cause drama-)

Senario #3 - Person A is sick (this can be like a normal sick or pregnancy sick btw .w.) And person B has to take care of them now

Senario #4 - Detroit: Become Human crossover B I T CH-