Thanksgiving has rolled around once again. Except this year, Winn and James are trying to work up the courage to tell Kara and Peter about their Guardian setup.

The group is at Kara's place setting up for the day and people still have the same question from their last get together. Gwen is spending this year with Peter and the group since they're finishing up the plans with their wedding soon.

"Have you guys chosen a date yet?" Winn asks Peter and Gwen.

"We were thinking sometime in the summer, somewhere romantic. Like a view of the ocean." Gwen tells them.

"Because nothin' soothes pre-wedding jitters like the thought of falling and drowning." Peter tells them. "On her part, not mine. She has been known to fall off of places. That's why I like to keep her away from bridges, last thing I need is her to snap her neck falling or something." He state and Gwen laughs.

"Wow...you two are the strangest and cutest couple I know." James comments to that as Mon-El has finally arrived so they can get to eating.

"Kara, would you do the honors?" Eliza asks.

"Oh, yes. Okay. So, it is a Danvers family tradition that before the meal, we go around and we say what we're thankful for, so..." Kara says and that all think that's a great idea.

James, Alex and Winn all stand up at once and James asks to go first.

"Kara, I for one would like to say, how thankful I am to have such an understanding friend." James says.

"He's right, you're so understanding." Winn agrees with him.

"No, she's not." Alex interrupts them.

"Oh boy." Gwen whispers to Peter seeing where this is going already.

That's where Mon-El steps in to toast. "Yeah, I just wanna...I just wanna say something. I'm also thankful for you, Kara. Because not only are you understanding, but you're also gracious. Out of everyone who could've found me in that pod, I'm the luckiest guy in the world that it was you. Oh, and you, Peter."

"I almost thought you forgot about me." Peter jokingly says.

"I'm just gonna jump in and say there are so many things that I'm thankful for." Alex says as she gets up and Mon-El sits back down. "And, honestly, I don't think I've ever really felt this much like myself than right now, and there's a reason for that. And that reason is..."

She gets interrupted when a blue portal opens up above the table and Peter's senses act weird as he hears voices.

"This might take a few tries." A male voice he's never heard before says.

"The Goblin is hunting down Spider-Men across the multiverse and you're his next target." A child like voice calls out as the portal closes.

"Hey, you okay?" Gwen asks seeing Peter acting nauseous as he grabs onto a chair for support.

"Does that normally happen on thanksgiving?" Mon-El asks.

-

"So, last night, the space time continuum ripped apart in the middle of your apartment." Winn says as they return to the DEO. "Which only makes it slightly less intense than last year's thanksgiving."

"Any idea what caused it?" Alex asks them.

"Maybe some extra-dimensional being just had a craving for your mom's cranberry relish." Gwen guesses.

"No, it was...strange." Peter tells them. "I heard voices. It was like...someone said something about a Goblin hunting down Spider-Men across the multiverse."

"And considering you're Spider-Man, that's bad news." Gwen says and promises to find a way of tracking it.

"All right, holidays over. Back to work." J'onn tells them. "Stacy was reviewing the footage of the deaths of our three alien weapon carriers and found someone interesting." He says and pulls up a photo of Lillian Luther.

"Lillian Luther was supposed to be in New York for some rich reason, so why is she in National City?" Peter asks them, rhetorically. "Because she has been seen everywhere there has been a Cadmus loose end."

"What? Lillian Luther?" Kara asks.

"I mean, we did just recently get her pain of a son Lex in prison recently." Gwen says from her computer.

"Which means she must have something bigger planned than these small jobs." Peter adds on since he had a few rounds with Lex over the years with Clark, and it seems that Lena might be the only good apple of the bunch of the Luther's. "Luther's are known for their over the top planning."

"Maybe I can learn what Lena knows." Kara says.

"Will do. I will tap every phone. I will hack every computer." Winn offers.

"No. I'll do it." Kara tells him. "I mean, I know her. I bet you I could get her to say what she knows."

"How do you plan on doing that, Skirt?" Peter asks.

"Reporting skills. And good old-fashion sneakiness." Kara tells him and they all look at her knowing she can't sneak around.

"You guys! I can be sneaky when I want to be." Kara defends herself.

"Yeah, okay." Peter says, completely disagreeing.

"Sounds like a plan." J'onn tells them and walks off and Kara is close behind.

"Start hacking, just to be safe." Peter tells Winn.

"One step ahead of you." Winn says and gets to work.

-

Mon-El was our getting drinks at the alien bar when he ran into someone who looked just like Hank, except half of his face was robotic and he released a gas that suffocated several people in there.

But to be safe, Mon-El has been placed under quarantine at the DEO.

"I feel fine. Like I could do 1,000 push-ups one handed." Mon-El tells them.

"While that's very impressive, we can't risk you transmitting whatever you were exposed to in the bar to the rest of us." J'onn explains to him.

"Which brings us to my question, what was he exposed to?" Peter asks.

"Explain what happened again." Kara asks Mon-El.

"I told you guys...I say you. But not you, I followed him outside, we fought and I lost. And I heard the screams. If I hadn't followed him outside, I could have stopped this." Mon-El tells them.

"The only reason you're still alive is because you chased him outside." Kara informs him.

"I have never heard of a weapon, Bio or otherwise, that targets only alien physiology." Gwen says as she did a complete search throughout everything that she could look into. "And that killed everyone in that bar, except for the humans."

"I would like to bring my mother in to help analyze the crime scene." Alex asks J'onn. "She specializes in astrobiology, I think she could really help."

"That's a good idea." J'onn agrees.

"Great, let's get going." Kara says.

"No, no, no." J'onn stops her. "You and I will remain quarantined here at the DEO until we can figure out exactly what sort of toxin we're dealing with." He tells her. "Parker's suit will protect him, right?" He asks Gwen.

"Yeah, it's airtight. I mean, the suit could survive the vacuum of space. But not the cold, that's why I worked on the Space-Spider." Gwen tells him.

"There's that and my DNA is half human, so I'll live." Peter tells them. "Don't worry, Skirt. You just stay safe." He says and leaves.

-

"Those voices that you've been hearing, I have a theory that's not gonna make any sense." Gwen tells Peter while Eliza is focusing on Mon-El who seems to have started choking after they left.

Which she was able to find out that the virus infecting people came from Krypton.

"What's the theory?" Winn asks her.

"What if they're voices of other Spider-Men throughout the multiverse? I mean, bear with me, what if you're hearing from their points of view? The voice saying someone is hunting Spider-Men, what if that was a warning from Spider-Man to another Spider-Man?" Gwen asks.

"If that's true, that means a Goblin is coming for me." Peter tells her.

"Peter," Kara comes in. "sorry to interrupt, but we need to get to the Fortress of Solitude." She tells him.

-

The two heroes fly as fast as they can to the fortress and they find fresh footprints in the snow.

Peter quickly does a scan and the foot length measurements line up with J'onn's, meaning Hank's been here.

"Kara Zor-El. Ho-Ren." Kelex greets the two of them.

"Kelex, what happened here?" Kara asks.

"There is a intruder in the Fortress." Kelex tells them.

Peter does a quick scene and doesn't find anyone. "I've got nothing." He tells Kara.

"Where? Who is it?" Kara asks Kelex.

"You. You are the intruder." Kelex tells them. "And you will be destroyed." He says before shooting at Kara.

Peter retaliates and shoots an EMP blast powerful enough to shut him down.

"Now we know someone's been here." Peter says as Kara and him walk up to the controls and sees someone was looking for something.

Kara does a scan for the latest search results and finds something Peter can't read.

"Project Medusa." Kara translates and activates to learn what it is.

A holographic projection of Kara's father appears.

"Hello, Kara. What do you wish to know?" He asks.

"What is Project Medusa?" Peter asks him.

"Medusa, a weaponized virus that I created for the defense of the planet Krypton." He informs them.

"A virus you created?" Kara asks her father.

"It was a joint partnership between the Science and Military Guilds. We bio-engineered the virus to attack non-Kryptonian physiology. In the event of an invasion, Medusa could be deployed to kill alien combatants while keeping our civilians and infrastructure safe from harm."

"Well, Cadmus must've done something to alter it from Kryptonian's to humans." Peter tells Kara.

"Growing up, you told me your work was to save lives." Kara tells her father.

"I was saving Kryptonian lives. It was the perfect weapon." He defends. "But the House of Ren deemed it too dangerous if it fell into enemy hands."

"Well, now it has done exactly that." Kara informs him and shuts it down.

"This could be even more problematic than before." Peter says and they need to inform J'onn on what they discovered.

-

"Henshaw stole the virus's formula from the Fortress of Solitude, which means Cadmus can make as much of the virus as they want." Kara tells J'onn and Alex.

"We should get Clark to add like a security password or something to the Fortress." Peter adds since it seems to be broken into easier and easier.

"An unstoppable bioweapon that kills every alien except Kryptonian's. The news just gets better and better." J'onn states sarcastically.

"Well, that explains why Mon-El is still alive. Kryptonian's And Daxamites shads simiar DNA." Alex adds.

"So, he'll recover?" Kara asks Eliza.

"His immune system is battling the virus and he is fighting hard. But without a cure, the infection will win." Eliza tells them.

"Well, here's what I downloaded from the Fortress." Peter says and hands them a hard drive. It took forever downloading alien tech to a tiny piece of human tech.

"Mom and I will get to work on it right away." Alex tells them.

Gwen is working on breaking the virus down while Winn has taken over her job on figuring out what that portal was since she's better at bioengineering.

"Okay, I've got the mainframe breaking down the virus on a molecular level so we should hopefully have an anti-virus ready in no time." Gwen tells the two of them and keeps watch.

-

Kara was looking out to the city from the DEO balcony and Peter joins her.

"I love this view. It's much better than the enclosed walls we had at the old base." Peter tells her. "And it's inside the city, so I don't need to constantly use my repulsers to get to and from and it's easier to just swing through the city. A lot more peaceful."

"Kinda reminds me of the view from my room on Krypton." Kara tells him. "I could see the whole city from that window. All the lights, pods zooming by..."

"Makes me wish I had some memory of the place." Peter tells her. "All I got was your weird It's a Wonderful Life thing from last year."

"Yeah, but I guess you didn't really see anything." Kara says and turns away. "All my life I thought my parents were the good guys. And now the more I learn, the more I see things, how they really are. And the more I'm ashamed to be their daughter."

"Skirt, your parents tried to keep the planet safe. Tried to keep people safe." Peter reminds her.

"I'm sure Lex and Lilian Luther thought their intentions were good, too." Kara replies. "Is this their legacy? Death and destruction across the universe?"

"Your parents, as well as mine don't end in their mistakes. They're making up for their mistakes through us. These aren't just symbols we wear, they resemble our strength. Everyone makes mistakes, but they didn't just make death and destruction, they made us. We're symbols of hope and justice. That's what their legacy's are." Peter tells her when Eliza and Alex approach them.

"We found out how Cadmus intends to weaponize Medusa." Alex tells the two of them.

"They need a dispersion agent, one not available on our planet, but there is an analogous element, Isotope 454." Eliza tells them.

"Which is incredibly rare because it's made exclusively by L-Corp. if Cadmus gets their hands on it, they'll be able to spread the gurus across the entire city." Alex finishes.

"Let's go pay Lena a visit, Skirt." Peter says and closes his mask and they take to the sky.

-

L-Corp, the Cyborg Hank has made his way in just in time for the two heroes to make it.

"I should have known you would show up." Cyborg Hank says.

"Yeah, were known for messing up bad guy plans." Peter quips and Kara speeds after him and Peter uses his repulsers from a distance to take him down when Lena comes out and Hank throws some debris at her.

Peter quickly activates a wrist missile and blasts the debris.

"Get out of here!" Peter warns her as the NCPD come in to help the heroes.

"All this time trying to save the world...who's gonna come and save you?" Hank asks Kara when Peter gets ready to aim a missile at Hank this time when another portal opens and Peter hears more voices.

"And I...am...Spider-Dad." A voice that sounds like an older Peter says.

"Rocket, I don't feel so good." More voices call in his head before it closes.

Kara uses the distraction to get the upper hand on cyborg Hank. Hank shoots a blast and Peter leaps in front of it to stop it from hitting Maggie.

They decide now to see if Lena actually knows anything or not about Cadmus and everything.

"You two know that doors not really an entrance, right?" Lena asks the two who just stare at her. Well, Kara stared, Peter just looked while crossing his arms. "I wanted to thank the two of you. Not only did you save the lives of countless numbers of my employees, but mine as well."

"Now I need something from you. We need help finding your mother." Kara tells her.

"Your mother is behind Cadmus." Peter informs her. "And now, she possesses a virus that can kill every alien in National City. If we don't find her, millions innocents will die."

"You know, I thought you were different. Wear those symbols and everyone thinks you're good. How many times did your cousin put on that high-and-mighty costume and come after Lex?" Lena asks Kara. "My mother may not be a saint, but you come in here and accuse her of being the Devil incarnate? How long before you come after me?"

"I know what it's like to be disillusioned by our parents. But I'm a pretty good judge of character. And you're not like your mother. She is cold and dangerous. And you are too good and too smart to follow in her path. Be your own hero." Kara tells her.

Lena either is a good liar as Winn suspected, or she doesn't know as Peter scans her facial muscles for anything and it seems that she doesn't know anything about her mother.

"You two can leave the same way you came in." Lena tells them.

"Come on, Skirt. She doesn't know anything, and we have a city to save." Peter tells her and they leave.

When the two of them left, Lena called her mother and Gwen overheard that Lena does "believe" in what Cadmus is doing now and she has her Isotope she needs.

-

"And now it seems Cadmus is getting prepared to release the virus at the port of National City." Gwen tells them after she tracks the signature.

"Why? The port isn't a drinkable water supply." Kara wonders.

"No, but it's the perfect place to launch the virus into the air. Disperse it right across National City." J'onn tells her.

"Tonight, our nightmare ends. Tonight, every alien who has stepped foot on our planet will die. Because earth is for the humans. The future is for the humans. We are Cadmus." Another video plays on their computers.

"You know, this show is growing on me." Peter jokes, seriously hating their videos and them being cocky.

"We have to move. Right now." J'onn tells them.

"Call Alex, get a strike team to meet us at the port now." Kara tells Winn.

"There's no time, it's just the three of us." J'onn tells her.

"J'onn, if either of you are exposed, you will die." Peter tells him.

"It's a fate I'm willing to accept." J'onn tells him. "If you two go, I'm watching your backs."

-

At the port, they have it ready to be dispersed inside of a rocket with Lena and Lillian ready to launch.

Before it could be released, the three heroes come down to stop them.

"Don't do it, Lena." Kara tells her.

"Why not? I'm a Luther." Lena tells them and turned the key and it takes off.

"I'll get the rocket, you two stop them." Peter says and takes off to the sky to stop it.

"You two are finished." J'onn tells them.

"You're wrong about that." Lillian tells them as cyborg Hank comes flying in and starts fighting them.

In the sky, Peter catches up with the rocket and starts hacking into it. But before he could get far, the bomb exploded sending Peter falling but gets caught by his safety-protocol.

The others just finished stopping cyber Hank and watch as the virus disperses across the city and wait for it to take effect, but nothing happens.

"They should be dead." Lillian states, completely confused. "All aliens should be dead." That's when she realized what Lena did. "You switched out the isotope. Made the virus inert."

"I did." Lena confirmed. "And I also called the police." She says as the NCPD make it.

Peter flew back and meets up with them. "Not that I'm not thankful we aren't, but shouldn't we be dead?" Peter asks them.

"Lena saved us." Kara informs him.

They were able to use what of the virus there was to save Mon-El so he will be okay now.

And apparently, M'gann was a White Martian and they were able to use the virus to fix him back to a Green Martin.

-

Back at Kara's place, an more stabilized breach opens and Cisco Ramon and Barry Allen of Earth-1 step out.

"This better be the right place." Cisco tells Barry.

"It is." Barry assures him as they look around the place.

"'Cause if this isn't the right place, someone's about to be real confused." Cisco says when the door opens and they turn to see Kara.

"Barry?" Kara asks, surprised to see him again.

"Hey, Kara." Barry greets his friend.

"I knew it. I knew that was you." Kara says closing her door and hugging her friend. "I knew it was you in that weird space portal thing."

"Yeah. It took a couple of tries to get here." Barry tells her. "This is my friend, Cisco." He introduces her to him.

"Hi." Cisco greets shaking her hand. "I've got to say, this is a nice universe you got here."

"Hey, do you remember last year, when I helped you and Peter out and you guys promised to do the same for me?" Barry asks her.

"What are we up against?" Kara asks him.

"You're gonna want to call Peter, that's for sure." Barry tells her.