Yep.
I made a Pokemon AU. It's still a work in progress, but so far I have:

Playable Characters: Cuphead or Mugman
Professor: Dr. Kahl
Character's mom: Elder Kettle
Nurse Joy: Legendary Chalice
Pokemart owner person: Porkrind
Gardening Supply Sellers: Root Pack
Daycare Worker: Sage
Gym Leaders:
Cagney (grass)
Ribby and Croaks (fighting)
Baroness Von Bonbon (fairy)
Wally Warbles (flying)
Grim Matchstick (dragon)
Rumor Honeybottoms (bug)
Cala Maria (water)
Blind Spectre (ghost)
Random ghost houses: 3 mausoleums/ Phantom Express
Champion: King Dice
Evil Team: The Devil and Dice's minions (Team Satanic)

Also, all characters are human in this AU.