I have seen certain writers with 20-30 thousand even 100k followers, and they haven't followed even one of them back or just a few. I have seen just as many likes and comments from their readers, and they haven't replied to one single comment from their readers. 

I always try my very best to reply back to my readers. It may not be in every chapter, but I do try and show my appreciation.  I never want one single of my readers thinking I'm stuck up or too good to acknowledge them. 

That will never happen. Lord knows I'm not the best writer, but the readers I do have, I always want them to know how grateful I am to have them.

Don't be a Karen writer. Show your appreciation.