How interferences work when people are discussing things;                                                                          Hello people : Author-Chan.                                                                                                                                              Helllo humanssSss : Orochimaru                                                                                                                                  Why am I here? :Other characters interrupting.

                                                                                               Titles:

Kun is used by a person of a higher status towards a younger person.  Friends can also refer to each other by kun in a casual context.

San, the most common one, could be translated as "Mr.", "Mrs." and "Ms." and is gender neutral.

Sama is the respectful version of san, mostly used in business and clientele context. This is since the implied superiority of the guest or customer is very strong.

Chan, the childish version of san, refers to children and girls. Chan, can also be used to refer to an endearing adult.  Chan is also frequently used to refer to cute animals and in particular, cats. 

I  am NOT childish!!!

Actually Author....

Shut it Snaky!!!

Alright. Then just get back to the information.

Senpai is often used in the English in the expression "Notice me senpai !!!" and its variants. Originally this was used in the context of a person hoping a crush or someone they admire will pay attention to them, but it has more broadly been used online in reference to famous people acknowledging a fan's existence.

Senpai in Japanese is used as acknowledgement to a mentor or someone who is your teacher.

Quote from the channel Mojo; "Orochimaru seems to treat death like a revolving door."

Too true XD

Hmph!!!