So, I always have musical crossover ideas in my head, so imagine if there was, like, a show like "Six" but it's the wives of Hamilton, Jefferson, Burr, Adams, Madison, and Jay (or Washington, as BlackGirlKK suggested)
I imagine that they would compete to see who had it the hardest with their husbands like in "Six" and an exchange in the show that would go like this:

Eliza: When my eldest son was only nineteen, he got shot in a duel... and DIED!

Martha Jefferson: OH, BOO HOO HOO! NINETEEN-YEAR-OLD  PHILIP DIED BY GETTTING SHOT BY A DUEL! WELL, I HAD NOT ONE, NOT TWO, NOT, THREE, BUT FOUR OUT OF SIX OF MY CHILDREN DIE, SO YOU DON'T GET TO TALK!

Or...

[After Eliza sings her song]
Abigail Adams: Eh... that's great and all, but that's not the most heart-wrenching song we've heard all night.

Eliza: Are you kidding? My husband cheated on me, then HUMILIATED me by writing a da**ed pamphlet about it, then my SON died in a duel! That's how much sh-- I had to go though!